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. 2023 Feb 2;14:1113932. doi: 10.3389/fimmu.2023.1113932

Figure 3.

Figure 3

Immunological memory phenotyping of CD62L+ T cells. Expression of CCR7 and CD45RA on CD62L+ CD4+ and CD8+ T cells (viable, CD14-, CD56-, CD19-, CD3+, CD4+ or CD8+ cells) in non-severe and severe COVID-19 patients, recovered COVID-19 patients, and healthy controls was assessed by flow cytometry. (A) Representative diagram and flow cytometry plots showing naïve CD4+ CD62L+ T cells (CCR7+ CD45RA+), central memory CD4+ CD62L+ T cells (CCR7+ CD45RA-), effector memory CD4+ CD62L+ T cells (CCR7- CD45RA-), and effector CD4+ CD62L+ T cells (CCR7- CD45RA+); (B) percentages of CD62L+ naïve, effector, central memory, and effector memory cells within the CD4+ T cell population; (C) percentages of CD62L+ naïve, effector, central memory, and effector memory cells within the CD8+ T cell population. *p<0.05, **p<0.01, ***p<0.001 one-way ANOVA with multiple comparisons correction.