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. 2023 Jan 25;3(2):100249. doi: 10.1016/j.xgen.2022.100249

Figure 4.

Figure 4

Summary of FDR-significant functional genes associated with PCT-stroke and PDW-PD trait pairs, with consistent direction of SMR effects

(A and B) PCT-stroke (A) and PDW-PD (B) trait pairs. The width of each line represents the SMR association strength. Line color indicates whether upregulation (orange) or downregulation (red) of functional genes is associated with increased disorder risk or BCT values. Genes with an asterisk symbol are known drug targets (Table S49). See Tables S36 and S37 for complete details of the SMR estimates.