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. 2023 Feb 16;11(2):e782. doi: 10.1002/iid3.782

Figure 5.

Figure 5

Treatment of GA‐regulated Th17/Treg‐related cytokines in the ankle joints of the mouse model of arthritis induced by collagen. The mRNA levels of IL‐6 (A), IL‐17A (B), IL‐10 (C), and TGF‐β (D) in the ankle joints were determined by using qPCR. (E) The protein expressions of those cytokines were determined by using Western blot analysis. (F–I) The relative expressions were normalized to the internal control (n = 3; eight tissue homogenates were mixed). *p < .05, **p < .01, and ***p < .001 as compared to the control. ## p < .01 and ### p < .001 as compared to the CIA group. GAH corresponded to the GA administration dosage of 80 mg/kg/d.