Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) Radical relay C—H functionalization involves an initial hydrogen atom transfer (HAT) mediated by a het2roatom-centered radical (X•) followed by the trapping of the carbon-centered radical with a redox-active metal complex. (B) Mechanism employed by natural non-heme iron enzymes for C(sp3)—H halogenation/azidation. (C) Integration of radical relay chemistry into non-heme iron enzymes enables unnatural C—H functionalization reactions.
