NCT02702856 |
prostate cancer |
determine the association
of an exosome urine test score with the presence of high Gleason grade/score
(GS >/= 7) prostate cancer on a prostate needle biopsy |
correlate an exosome gene expression signature
with the presence or absence of high grade prostate cancer in the
prostate needle biopsy |
NCT03830619 |
lung cancer |
investigate
the sensitivity and specificity of serum exosome
noncoding RNA as a biomarker for the diagnosis of lung cancer |
the expression levels of serum exosome long noncoding RNA |
the expression
levels of tumor biomarkers |
the CT scans of
the lung for the patients |
NCT03895216 |
bone metastases |
obtain
a panel of biomarkers predictive of bone
metastasis |
changes in miRNAs content of circulating
tumor exosomes |
changes in protein content
of circulating tumor exosomes |
NCT03032913 |
pancreatic cancer |
determining whether
liquid biopsy approaches are valid in the diagnosis of pancreatic
cancer |
sensitivity of CTC detection with 3 methods in
cell spiking experiments |
diagnostic accuracy
of the best CTC detection method and onco-exosome
quantification for pancreatic adenocarcinoma diagnosis |
NCT04720599 |
urologic cancer |
confirm the performance of the ExoDx prostate gene expression assay
in patients presenting for an initial prostate biopsy |
correlation of the ExoDx prostate test results with the outcome
of prostate biopsies in an initial biopsy patient cohort |
NCT03911999 |
prostate
cancer |
investigate the
relationship of urinary exosome and the aggressiveness of prostate
cancer |
differences in microRNA expression between nonprostate
cancer subjects, pathologically insignificant, and significant prostate
cancer patients |
the accuracy of selected
microRNAs for
the differentiation of patients with pathologically insignificant
and significant prostate cancer after radical prostatectomy |
NCT03031418 |
prostate cancer |
a new and validated urine test which predicts the likelihood
of
high grade prostate cancer on an initial prostate biopsy |
confirm performance of the ExoDx Prostate IntelliScore |
NCT02862470 |
thyroid cancer |
analyze the urine exosomal proteins and probable biological markers,
then find the prognostic biological markers |
prognostic
biological markers via this prospective study. |
NCT05101655 |
lung metastasis of
osteosarcoma |
use exosome microfluidic
chips to establish a combination of exosome subgroup level (exosome
barcode) markers for the early diagnosis of osteosarcoma lung recurrence |
the association of disease recurrence with
plasma levels of exosome and its subgroups |
NCT05334849 |
advanced gastric
carcinoma |
verify the function of circulating exosomal
lncRNA-GC1 on predicting
and monitoring immunotherapeutic outcomes of GC |
levels
of circulating exosomal lncRNA-GC1 |