Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 15;23:27. doi: 10.1186/s12935-023-02866-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 3 — Knockdown of CCL14-AS promotes invasiveness and lymph node metastasis of CRC cells. A Detection of CCL14-AS level by qRT-PCR in CCL14-AS-konckdowned HCT116 and RKO cells. B, C Wound healing assay showing cell migration of HCT116 and RKO cells with or without CCL14-AS knockdown. Scale bar: 100 μm. D Migration and invasion of HCT116 and RKO cells with or without CCL14-AS knockdown were evaluated by using transwell assays. Scale bar: 500 μm. E Popliteal lymph nodes volume and size were significantly increased in the CCL14-AS knockdown group compared with the control group. F Representative images of the lymph node stained with H&E (left) in the CCL14-AS knockdown group. Scale bar: 100 μm. Statistical results of the metastatic ratios of lymph nodes in the Scramble control and CCL14-AS knockdown group (right). * p < 0.05, ** p < 0.01, *** p < 0.001