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. 2023 Feb 16;22:33. doi: 10.1186/s12943-023-01741-x

Fig. 4.

Fig. 4

Small extracellular vesicle (sEV) miRNA biomarkers in breast cancer (BC) diagnosis, prognosis, chemoresistance. BC plasma and cell supernatant samples are collected, and the isolated sEVs containing miRNAs are analysed by reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR), next-generation sequencing (NGS), and microarray analysis. The unique sEV miRNA expression profiles of BC samples have value for diagnosis, prognosis, and predicting chemoresistance of BC. This figure was created with BioRender.com