| Ruiz‐Pomeda 2018 |
Low risk of bias |
Central registration system, permuted block method. Everyone masked to CL assignment until after study completion. There were no baseline imbalances that would suggest a problem with randomisation. |
Low risk of bias |
It was not possible to mask the children or carers given the nature of the interventions. The differences at baseline were subjected to analysis of variance. |
Low risk of bias |
Outcome data were available for nearly all randomised participants. |
Low risk of bias |
Appropriate and comparable methods of measuring outcome data were used. |
Some concerns |
Protocol registered. Not enough information in the protocol on a statistical plan and no published statistical plan used. |
Some concerns |
The study is judged to raise some concerns in at least one domain for this result, but not at high risk of bias for any domain. |
