. 2023 Jan 31;8(6):5983–5994. doi: 10.1021/acsomega.2c07907

Table 1. Efficacy on GPBAR1 and RORγt^a ^b ^c.

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Eff. (%) is the maximum efficacy of the compound (10 μM) relative to TLCA (10 μM) as 100 in transactivation of a cAMP-responsive element (CRE) on HEK-293T cells; results are the mean of two experiments ± SD.

Eff. is the efficacy of the compound (10 μM) as % of inhibition calculated from the residual activity of RORγt, defining the wells containing only vehicle (DMSO) as 100% control and the wells without the protein as 0% control.

nt means not tested.

Table 1. Efficacy on GPBAR1 and RORγtabc.

Table 1. Efficacy on GPBAR1 and RORγt^a ^b ^c.