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. 2023 Feb 6;8(6):5571–5592. doi: 10.1021/acsomega.2c06954

Table 1. IC50 Values of Compounds 3ae against MCF-7 and HePG-2 Cell Lines.

compound no. R IC50 in μg/mL MCF-7 IC50 in μg/mL HePG-2
doxorubicin   4.17 ± 0.2 5.57 ± 0.4
3a H 52.11 ± 3.1 65.75 ± 3.3
3b Me 56.27 ± 3.4 62.16 ± 3.2
3c OMe 37.59 ± 3.4 31.22 ± 2.6
3d Cl 30.84 ± 2.2 38.20 ± 2.7
3e Br 11.16 ± 1.5 10.66 ± 1.0