Table 1. IC50 Values of Compounds 3a–e against MCF-7 and HePG-2 Cell Lines.
| compound no. | R | IC50 in μg/mL MCF-7 | IC50 in μg/mL HePG-2 |
|---|---|---|---|
| doxorubicin | 4.17 ± 0.2 | 5.57 ± 0.4 | |
| 3a | H | 52.11 ± 3.1 | 65.75 ± 3.3 |
| 3b | Me | 56.27 ± 3.4 | 62.16 ± 3.2 |
| 3c | OMe | 37.59 ± 3.4 | 31.22 ± 2.6 |
| 3d | Cl | 30.84 ± 2.2 | 38.20 ± 2.7 |
| 3e | Br | 11.16 ± 1.5 | 10.66 ± 1.0 |