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. 2023 Feb 6;8(6):5571–5592. doi: 10.1021/acsomega.2c06954

Table 2. IC50 Values of Compounds 5a and 5dg against MCF-7 and HePG-2 Cell Lines.

compound no. R X IC50 in μg/mL MCF-7 IC50 in μg/mL HePG-2
doxorubicin     4.17 ± 0.2 5.57 ± 0.4
5a H H 30.30 ± 0.4 38.42 ± 2.1
5d Me H 25.95 ± 2.8 21.31 ± 1.8
5e OMe H 35.72 ± 72 30.70 ± 0.3
5f Cl H 25.40 ± 2.1 29.0 ± 2.1
5g Br H 42.91 ± 2.7 44.96 ± 3.0