Table 2. IC50 Values of Compounds 5a and 5d–g against MCF-7 and HePG-2 Cell Lines.
| compound no. | R | X | IC50 in μg/mL MCF-7 | IC50 in μg/mL HePG-2 |
|---|---|---|---|---|
| doxorubicin | 4.17 ± 0.2 | 5.57 ± 0.4 | ||
| 5a | H | H | 30.30 ± 0.4 | 38.42 ± 2.1 |
| 5d | Me | H | 25.95 ± 2.8 | 21.31 ± 1.8 |
| 5e | OMe | H | 35.72 ± 72 | 30.70 ± 0.3 |
| 5f | Cl | H | 25.40 ± 2.1 | 29.0 ± 2.1 |
| 5g | Br | H | 42.91 ± 2.7 | 44.96 ± 3.0 |