FIG 5.

panIrgm^−/− mice survival phenotype after long-term Mtb infection. WT or panIrgm^−/− mice were infected with H37Rv Mtb by the aerosol route in the same batch as Fig. 3 and 4 (day 1, 200 to 250 CFU). Relative survival of WT and panIrgm^−/− mice following Mtb infection by the aerosol route (Mantel-Cox test; **, P < 0.01). Data are from one experiment with 12 to 18 male mice per group.