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. 2023 Jan 17;67(2):e01276-22. doi: 10.1128/aac.01276-22

FIG 2.

FIG 2

Iohexol GFR comparison for rats in the variable vancomycin dose arm, between treatment groups and across dosing days. Using the AKI positive-control group as the reference group, the GFR was significantly higher in both the low- and high-VAN-dose group rats on all dosing days (a, 0.33 mL/min/100 g of body weight [95% CI, 0.22 to 0.44 mL/min/100 g of body weight] [P < 0.001]; b, 0.34 mL/min/100 g of body weight [95% CI, 0.23 to 0.45 mL/min/100 g of body weight] [P < 0.001]; c, 0.29 mL/min/100 g of body weight [95% CI, 0.18 to 0.40 mL/min/100 g of body weight] [P < 0.001]; d, 0.39 mL/min/100 g of body weight [95% CI, 0.29 to 0.51 mL/min/100 g of body weight] [P < 0.001]; e, 0.21 mL/min/100 g of body weight [95% CI, 0.09 to 0.32 mL/min/100 g of body weight] [P < 0.001]; f, 0.22 mL/min/100 g of body weight [95% CI, 0.11 to 0.33 mL/min/100 g of body weight] [P < 0.001]; g, 0.24 mL/min/100 g of body weight [95% CI, 0.13 to 0.35 mL/min/100 g of body weight] [P < 0.001]; h, 0.26 mL/min/100 g of body weight [95% CI, 0.15 to 0.37 mL/min/100 g of body weight] [P < 0.001]).