Table 2.
Incidence of New Conditions and Symptoms Among COVID-19-Positive and COVID-19-Negative Patients, by COVID-19 and Hospitalization Status
| COVID-19 positive (%) | COVID-19 negative (%) | |||||
|---|---|---|---|---|---|---|
| All (N = 62,339) | Hospitalized (N = 13,106) | Non-hospitalized (N = 49,233) | All (N = 247,881) | Hospitalized (N = 71,222) | Non-hospitalized (N = 176,659) | |
| Nervous | ||||||
| Encephalopathy | 1.7 | 3.3 | 1.2 | 1.1 | 2.2 | 0.6 |
| Dementia | 0.9 | 3.1 | 0.4 | 0.8 | 2.1 | 0.4 |
| Cognitive problems | 3.8 | 6.9 | 3.1 | 2.7 | 4.7 | 2.0 |
| Sleep disorders | 3.7 | 4.8 | 3.4 | 2.7 | 2.9 | 2.7 |
| Headache | 3.5 | 3.2 | 3.6 | 2.4 | 2.3 | 2.4 |
| Any nervous condition | 10.3 | 14.8 | 9.2 | 7.6 | 10.2 | 6.6 |
| Skin | ||||||
| Hair loss | 1.2 | 1.1 | 1.2 | 0.6 | 0.4 | 0.6 |
| Pressure ulcer of skin | 0.6 | 2.4 | 0.2 | 0.5 | 1.3 | 0.1 |
| Any skin conditions | 1.8 | 3.5 | 1.4 | 1.0 | 1.7 | 0.8 |
| Respiratory | ||||||
| Lower respiratory disease | 2.7 | 5.3 | 2 | 1.1 | 1.5 | 0.9 |
| Dyspnea | 11.8 | 16.8 | 10.5 | 6.4 | 7.4 | 6.0 |
| Upper respiratory infections | 1.3 | 1.1 | 0.9 | 0.9 | 0.6 | 1.0 |
| Any respiratory condition | 13.4 | 18.9 | 11.9 | 7.3 | 8.1 | 6.9 |
| Circulatory | ||||||
| Pulmonary embolism | 0.8 | 2.3 | 0.4 | 0.5 | 1.1 | 0.3 |
| Thromboembolism | 1.3 | 3.2 | 0.8 | 1.0 | 2.0 | 0.6 |
| Chest pain | 5.8 | 6.5 | 5.6 | 3.7 | 3.9 | 3.6 |
| Abnormal heartbeat | 5.3 | 7.6 | 4.7 | 3.3 | 4.6 | 2.9 |
| Any circulatory condition | 10.6 | 15.4 | 9.5 | 7.1 | 9.4 | 6.3 |
| Blood | ||||||
| Anemia | 4.2 | 9.4 | 3.0 | 3.7 | 7.2 | 2.4 |
| Endocrine | ||||||
| Malnutrition | 1.6 | 4.8 | 0.7 | 1.4 | 3.3 | 0.7 |
| Diabetes mellitus | 3.1 | 6.8 | 2.3 | 2.7 | 4.3 | 2.1 |
| Fluid and electrolyte disorders | 0.5 | 1.6 | 0.3 | 0.4 | 0.9 | 0.2 |
| Edema | 6.6 | 10.5 | 5.6 | 5.5 | 7.6 | 4.7 |
| Any endocrine condition | 9.4 | 17.6 | 7.8 | 8.1 | 11.8 | 6.7 |
| Digestive | ||||||
| Other constipation | 3.7 | 6.3 | 3.0 | 3.6 | 4.9 | 3.1 |
| Abdominal pain | 8.4 | 10.1 | 8.0 | 7.3 | 8.3 | 6.9 |
| Any digestive condition | 10.2 | 13.8 | 9.3 | 9.0 | 10.9 | 8.2 |
| General signed and symptoms | ||||||
| Malaise and fatigue | 4.9 | 7.8 | 4.2 | 3.3 | 4.6 | 2.8 |
| Fever | 0.2 | 0.5 | 0.1 | 0.2 | 0.3 | 0.1 |
| Joint pain | 10.0 | 10.8 | 9.8 | 8.1 | 8.2 | 8.0 |
| Any general signed and symptoms | 13.4 | 16.0 | 12.7 | 10.6 | 11.7 | 10.1 |
Notes: When calculating the incidence of each new condition and symptom, the denominator is the number of COVID-19-positive patients without any diagnosis of the condition or symptom at baseline and the numerator is the number of COVID-19 patients without the diagnosis at baseline but with at least one diagnosis of the condition or symptom in the follow-up period. p values indicate the statistical significance of differences in PASC incidence comparing COVID-19-positive and COVID-19-negative patients, using χ2 tests.