TABLE 1.

The effect of solvent, temperature and base in the Suzuki reaction.

Entry	Solvent	Base	Cat. (mol%)	T (°C)	Time (min)	Yield (%)
1	H2O	K2CO3	0.04	50	30	83
2 a	H2O	K2CO3	0.08	50	30	96
3	H2O	K2CO3	0.16	50	30	96
4	H2O	K2CO3	0.08	r.t.	30	Trace
5	H2O	K2CO3	0.08	40	30	60
6	H2O	K2CO3	0.08	65	30	96
7 b	H2O	K2CO3	0.08	50	30	75
8	EtOH	K2CO3	0.08	50	30	82
9	Toluene	K2CO3	0.08	50	30	55
10 c	H2O/EtOH	K2CO3	0.08	50	30	88
11	H2O	NaOAc	0.08	50	30	78
12	H2O	NEt3	0.08	50	30	67
13	H2O	NaOH	0.08	50	30	60
14	H2O	Base-free	0.08	50	60	Trace
15 d	H2O	K2CO3	0.004 g	50	60	—
16 e	H2O	K2CO3	0.004 g	50	60	—

^a Optimum conditions.

^b The reaction was performed in an oil bath.

^c EtOH:H₂O (1:1).

^d Fe₃O₄@PMO/SB was used as catalyst.

^e Fe₃O₄@PMO was used as catalyst.