Skip to main content
. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Comput Toxicol. 2022 Jul 14;24:100237. doi: 10.1016/j.comtox.2022.100237

Table 4.

Summary of different sources of in vivo acute toxicity data

Source Study type Endpoint Number of unique chemicals
RTECS Rat oral LD50 16,499
RTECS Rat dermal LD50 1,267
RTECS Rat inhalation LD50 1,718
RTECS Mouse oral LD50 34,522
RTECS Mouse dermal LD50 264
RTECS Mouse inhalation LD50 915
RTECS Rabbit dermal LD50 5,321
CFSAN/PAFA Rat oral LD50 949
CFSAN/PAFA Mouse oral LD50 366
ECHA (ChemProp) Rat oral LD50 2,136
JRC AcutoxBase Rat oral LD50 138
NLM HSDB Rat oral LD50 2,205
OECD (eChemPortal) Rat oral LD50 2,290
PAI (NICEATM) Rat oral LD50 293
TEST (NLM ChemIDplus) Rat oral LD50 12,974