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. Author manuscript; available in PMC: 2023 Feb 16.
Published in final edited form as: Epilepsy Behav. 2022 Oct 27;137(Pt A):108951. doi: 10.1016/j.yebeh.2022.108951

Figure 2: Individual Seizure Frequency Reduction and Responder Rate –

Figure 2:

(a) Individual seizure frequency reduction (n = 159) from worse (upper left) to best (upper right). Each bar is color coded by neuromodulation strategy. The segment with no bars represents patients who had no change in seizure frequency (6 ANT-DBS patients, 5 CM-DBS patients, 2 RNS patients, 2 CSS patients and 7 VNS patients). (b) MSR was not different across neuromodulation strategies at the group level, although CSS was associated with an improved MSR compared to ANT-DBS, CM-DBS, RNS, and VNS in pairwise comparisons (* indicates p values < 0.05, unadjusted). (c) Responder rates and seizure freedom over past 3 months.

ANT-DBS, anterior thalamic nuclei deep brain stimulation; CM-DBS, centromedian thalamic nuclei deep brain stimulation; CSS, chronic subthreshold stimulation; RNS, responsive neurostimulation; VNS, vagus nerve stimulation