Figure 1 |.

Symptoms during perimenopause. Perimenopause is characterized by heightened variability in neurological symptoms, which is co-incident with a decline in glucose metabolism in the brain. a | Variability of symptoms in premenopause, perimenopause and postmenopause (blue line; left axis); glucose metabolism in the brain (red line; right axis). b | Diversity of neurological symptoms during perimenopause. The majority of women will experience neurological symptoms during perimenopause; however, a small proportion (~20%) of women will transition without symptoms.