Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of results—adhesion and intracellular signaling are both required for synapse organization. (A) Adhesion by Nrxns and Nlgns can drive synapse organization which is blocked (B) when the binding interface between Nlgn1 and Nrxns is disrupted. (C) Barnoligin and Starexin can drive synapse organization through adhesion but synapse organization is blocked (D) by the replacement of the Nrx-3β intracellular domain with a GPI anchor.
