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. 2023 Feb 16;18(2):e0279105. doi: 10.1371/journal.pone.0279105

Table 2. Overview of overall ED utilization during COVID waves and reference periods in 2019.

First wave Reference period first wave  Second wave Reference period second wave  p value first wave vs reference  p value second wave vs reference  p value first vs second wave
Total number of patients, n (%) 18,024 (14.7%) 22,607 (18.4%) 18,282 (14.9%) 21,557 (17.6%) <0.001 <0.001 0.608
Age in years, median (IQR)  62 (39–76) 59 (32–75) 62 (37–76) 60 (33–76) <0.001  <0.001 0.011 
Sex (missing = 23)          
Female, n (%) 8,722 (48.4%) 11,242 (49.7%) 8,867 (48.5%) 10,697 (49.7%) <0.001 <0.001 0.754
Male, n (%) 9,298 (51.6%) 11,363 (50.3%) 9,415 (51.5%) 10,856 (50.3%) <0.001 <0.001 0.866
Possible COVID, n (%) 4,777 (26.5%) 0 (0%)  3,102 (17.0%) 0 (0%)  - - <0.001
Transportation to ED: Ambulance
Self-referral, n (%) 3,801 (21.1%) 3,716 (16.7%) 4,053 (22.2%) 3,745 (17.8%) 0.811 <0.007 <0.044
GP, n (%) 2,924 (16.3%) 3,110 (14.0%) 2,744 (15.0%) 3,035 (14.4%) 0.125 <0.002 0.126
Transportation to ED: Own transport
Self-referral, n (%) 877 (4.9%) 1,402 (6.3%) 966 (5.3%) 1,287 (6.1%) <0.001 <0.001 0.231
GP, n (%) 8,324 (46.2%) 11,192 (50.4%) 8,079 (44.2%) 10,353 (49.1%) <0.001 <0.001 0.301
Other, n (%) 2,081 (11.6%) 4,222 (19.0%) 2,432 (13.3%) 2,675 (12.7%) <0.001 <0.009 <0.001
Urgency of ED visit*        
high urgency, n (%) 3,823 (22.9%) 4,247 (19.8%) 3,817 (22.6%) 4,169 (20.5%) <0.001 <0.001 >0.999
low urgency, n (%) 12,847 (77.1%) 17,125 (80.2%) 13,043 (77.4%) 16,182 (79.5%) <0.001 < 0.001 0.686
Trauma, n (%) (missing = 1) 4,933 (27.4%) 7,375 (32.6%) 5,251 (28.7%) 6,916 (32.1%) <0.001 <0.001 0.004
Median minutes spent in ED, m (IQR) 157 (105–219) 147 (94–208) 154 (99–215) 147 (96–207) <0.001 <0.001 <0.001
Admission after ED visit, n (%) (missing = 15650) 8,990 (57.3%) 10,490 (52.3%) 8,674 (56.7%) 10,146 (46.3%) <0.001 <0.001 0.218

if the total number of patients does not match the total of inclusions, this is due to missing value

* using the MTS, red or orange triage colour are classified as high urgency (seen by doctor <10 minutes) and triage colour yellow, green or blue are classified as low urgency (1–3 hours before assessment)

**After Bonferroni correction a p-value of 0.003 was considered statistically significant.

IQR = interquartile range