Table 1.

Commercially available bioreactor systems for cell and tissue culture under fluid flow conditions. These table has a representation of different systems and is not exhaustive, with a wide range of different systems available for specific applications. ALI = Air-Liquid Interface, ECM = Extracellular Matrix.

Manufacturer	System	Bioreactor Type	Set-up	Volume per culture	Basic Control Functions	Cell location	Refs.
Synthecon	Rotary Cell Culture System	Rotary	Single, dual, or quad rotary vessels	Customizable	Rotation speed	In suspension or on microcarriers	[33]
CelVivo	ClinoStar™ / ClinoReactor™	Rotary	Six rotary vessels in a stand-alone incubator	10 mL	Rotation Speed Temperature CO2 Level	In suspension or on microcarriers	[30]
Reprocell	Alvetex® Perfusion Plate	Pumped	Plate with 4 interconnected wells	10 mL	Flow rate	In scaffold, submerged or at ALI	[34]
Kirkstall	Quasi Vivo®	Pumped / Microfluidic	Single or multiple connected chambers	2 - 4 mL	Flow rate	In scaffold, submerged or at ALI, barrier model option	[35]
ibidi	Pump System	Pumped / Microfluidic	Microslides with chambers	60 µL	Flow rate	Channel surface	[36]
Emulate	Human Emulation System	Pumped / Microfluidic	Stretchable dual channel microchips with a porous membrane	15 - 35 µL	Flow rate Cyclic stretch	Porous membrane, channel surface	[31]
ABLE® Biott®	Magnetic Stir System	Stirred	Impeller stirred bioreactors	5 −100 mL	Stir speed	In suspension or on microcarriers	[37]
Corning™	Spinner Flasks	Stirred	Impeller stirred bioreactors	125 mL – 36 L	Stir speed	In suspension or on microcarriers	[38]
Mimetas	OrganoFlow® / OrganoPlate®	Rocked / Microfluidic	Multichannel microchips with oscillatory perfusion	50 µL	Rocker speed Rocker angle	On channel surface, on or in ECM	[39]