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[Preprint]. 2024 Jan 9:2023.02.06.527311. Originally published 2023 Feb 7. [Version 2] doi: 10.1101/2023.02.06.527311

Figure 4. Low Ile and Low AA diet ameliorates multiple molecular indicators of aging rate in the liver.

Figure 4.

(A–D) Diet and age alters aging rate indicators related to (A) mTOR signaling, (B) MAPK ERK signaling, (C) capindependent translation (CIT), and (D) lipid oxidation in the liver of male mice. (E–H) Diet and age alters aging rate indicators related to (E) mTOR signaling, (F) MAPK ERK signaling, (G) cap-independent translation (CIT), and (H) lipid oxidation in the liver of female mice. (I) Representative Western blots of the proteins analyzed. n=6/group, ANOVA followed by Dunnet’s test. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. Data presented as mean ± SEM.