Figure 4.
Mitochondrial physiology is altered in shFXN. (A) Mitobright mitochondrial dye is used to determine the number of mitochondrial objects per cell. (B) Mitochondrial number is normalized to the cell area to determine the percentage cytosolic occupancy. (C) Total cell size is quantified and normalized to EVEC controls. Student’s T-test α =0.05 * p < 0.05, **** p < 0.0001. (A) EVEC; n = 71, shFXN; n = 105. (C) EVEC; n = 71, shFXN; n = 106 (B). EVEC; n = 71, shFXN; n = 105. Each representative of 3 biological replicates.
