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[Preprint]. 2023 Feb 7:2023.02.02.23285393. [Version 1] doi: 10.1101/2023.02.02.23285393

Figure 4. Associations of COVID-19 symptoms with age and progression to severe disease.

Figure 4.

A. Frequency of COVID-19 symptoms according to age. The shade colour of the cells is linked to the high and low percentage values. B. Associations between age and symptom likelihood. Multivariate analysis used each symptom as an outcome and mutant strain, age (elderly or non-elderly), body mass index, underlying disease, vaccination history, and history of spontaneous infection as explanatory variables. Elderly individuals (age ≥ 65 years) and the adjusted odds ratio (OR) for each symptom are arranged from highest to lowest. C. OR for COVID-19 symptoms and progression to severe disease. Multivariate analysis was performed using progression to severe disease as an outcome and mutant strain, age, body mass index, underlying disease, vaccination history, history of previous infection, and all symptoms as explanatory variables. Symptoms are sorted in descending order of OR for progression to severe disease. Points indicate ORs, and bars indicate 95% confidence intervals. The detailed results of the multivariate analysis are presented in Table S4.