Table 1.
Aberrant Behavior Checklist (ABC) Hyperactivity subscale and two subdomain scores by characteristics of 574 CHARGE children.
| Characteristicsa | All children (n = 574) | Aberrant Behavior Checklist (ABC) | ||||||
|---|---|---|---|---|---|---|---|---|
| Hyperactivity subscaleb (n = 515) | Hyperactivity/impulsivity subdomainb (n = 520) | Inattention subdomainb (n = 547) | ||||||
| Freq (%) | Median (IQR) | p-valuec | Median (IQR) | p-valuec | Median (IQR) | p-valuec | ||
| Sex | 0.48 | 0.41 | 0.72 | |||||
| Male | 460 (80.1) | 7.0 (1.0, 18.8) | 4.0 (1.0, 11.0) | 2.0 (0.0, 3.8) | ||||
| Female | 114 (19.9) | 6.0 (1.0, 19.0) | 3.0 (0.0, 10.0) | 2.0 (0.0, 4.0) | ||||
| Child’s birth year | 0.008 | 0.004 | 0.008 | |||||
| 2000–2004 | 160 (27.9) | 5.0 (1.0, 14.5) | 3.0 (0.0, 10.0) | 1.0 (0.0, 3.0) | ||||
| 2005–2008 | 227 (39.5) | 6.0 (1.0, 15.0) | 3.0 (0.0, 10.0) | 1.0 (0.0, 3.0) | ||||
| 2009–2013 | 187 (32.6) | 10.0 (3.0, 20.5) | 6.0 (1.5, 13.5) | 2.0 (0.0, 4.0) | ||||
| Preterm birth (< 37 weeks) | 0.06 | 0.08 | 0.07 | |||||
| No | 503 (87.6) | 7.0 (1.0, 17.5) | 4.0 (0.0, 10.0) | 1.5 (0.0, 4.0) | ||||
| Yes | 60 (10.5) | 10.0 (3.3, 24.0) | 6.0 (1.0, 14.3) | 2.0 (1.0, 4.0) | ||||
| Child’s race/ethnicity | 0.01 | 0.01 | 0.04 | |||||
| White (non-Hispanic) | 279 (48.6) | 5.0 (1.0, 16.0) | 3.0 (0.0, 10.0) | 1.0 (0.0, 3.0) | ||||
| Non-White (non-Hispanic) | 120 (20.9) | 10.0 (2.0, 24.5) | 6.0 (1.0, 16.0) | 2.0 (0.0, 4.0) | ||||
| Hispanic (any race) | 170 (29.6) | 7.5 (1.0, 15.0) | 4.0 (1.0, 10.0) | 2.0 (0.0, 3.0) | ||||
| Mother’s age at delivery | 0.004 | 0.009 | 0.008 | |||||
| < 30 years | 255 (44.4) | 8.0 (1.0, 20.5) | 4.0 (1.0, 13.0) | 1.0 (0.0, 4.0) | ||||
| 30–34 years | 179 (31.2) | 4.0 (0.5, 12.5) | 2.0 (0.0, 8.0) | 1.0 (0.0, 3.0) | ||||
| ≥ 35 years | 140 (24.4) | 10.0 (3.0, 17.0) | 5.5 (1.3, 10.0) | 2.0 (0.0, 4.0) | ||||
| Maternal metabolic conditions | 0.03 | 0.03 | 0.03 | |||||
| Healthy weight/overweight and no metabolic conditions | 366 (63.8) | 6.0 (1.0, 16.0) | 3.0 (0.0, 10.0) | 1.0 (0.0, 3.0) | ||||
| Obese or hypertensive disorder/gestational diabetes | 192 (33.4) | 8.0 (2.0, 21.8) | 6.0 (1.0, 14.0) | 2.0 (0.0, 4.0) | ||||
| Parity | < 0.001 | < 0.001 | < 0.001 | |||||
| 1 | 233 (40.6) | 9.0 (3.0, 22.0) | 6.0 (1.0, 14.0) | 2.0 (0.0, 4.0) | ||||
| ≥ 2 | 322 (56.1) | 5.0 (1.0, 14.0) | 2.0 (0.0, 9.3) | 1.0 (0.0, 3.0) | ||||
| Highest education in household | < 0.001 | < 0.001 | < 0.001 | |||||
| High school/GED or less | 60 (10.5) | 20.5 (8.5, 28.0) | 12.0 (5.0, 19.0) | 3.0 (2.0, 5.0) | ||||
| Some college credit | 189 (32.9) | 7.0 (1.0, 16.8) | 4.0 (1.0, 10.0) | 2.0 (0.0, 3.0) | ||||
| Bachelor’s degree or higher | 325 (56.6) | 5.0 (1.0, 15.0) | 3.0 (0.0, 10.0) | 1.0 (0.0, 3.0) | ||||
| Homeowner | 0.008 | 0.007 | 0.002 | |||||
| No | 172 (30.0) | 9.0 (2.0, 22.3) | 5.0 (1.0, 15.0) | 2.0 (0.0, 4.0) | ||||
| Yes | 381 (66.4) | 6.0 (1.0, 15.8) | 3.0 (0.0, 10.0) | 1.0 (0.0, 3.0) | ||||
| Diagnostic groups | < 0.001 | < 0.001 | < 0.001 | |||||
| ASD | 232 (40.4) | 19.0 (10.0, 27.0) | 11.0 (5.0, 18.0) | 4.0 (2.0, 5.0) | ||||
| DD | 94 (16.4) | 8.5 (3.5, 19.0) | 5.0 (2.0, 11.5) | 2.0 (1.0, 4.0) | ||||
| TD | 248 (43.2) | 1.0 (0.0, 5.0) | 1.0 (0.0, 3.0) | 0.0 (0.0, 1.0) | ||||
| Mean (SD) | rspd | p-valuee | rspd | p-valuee | rspd | p-valuee | ||
| Child’s age at assessment | 3.9 (0.7) | 0.12 | 0.005 | 0.13 | 0.004 | 0.11 | 0.01 | |
a
Missing (n): preterm birth (11), child’s race/ethnicity (5), maternal metabolic condition (16), parity (19), homeowner (21)
b
Mean ± SD for each subscale or subdomain score in the whole study population: 10.8 ± 11.4 for Hyperactivity subscale, 6.9 ± 7.6 for hyperactivity/impulsivity subdomain, 2.2 ± 2.3 for inattention subdomain
c
P-values from the Wilcox rank-sum test or the Kruskal-Wallis test.
d
Spearman’s rank correlation coefficients between child’s age and ABC scores or DEP concentrations.
e
P-values from the significance test of Spearman’s rank correlation coefficient.