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[Preprint]. 2023 Feb 11:2023.02.10.23285762. [Version 1] doi: 10.1101/2023.02.10.23285762

Figure 2: MPRA identifies regulatory variants with allele-specific effects on gene expression.

Figure 2:

(A) Diagram describing design of MPRA (also see Methods). (B) Distribution of significant changes in allele-specific transcriptional activity across all SNVs. (C) Number of MPRA SNVs showing significant (Adj. p<0.05) changes in allele-specific transcriptional activity in each ALL cell line. (D) Pair-wise linear correlation between changes in allele-specific transcriptional activity for all significant (Adj. p<0.05) changes across all cell lines. R2 correlation and p-value are provided.