Table 2. Response rates achieved, resectability at the end of three cycles and toxicity analysis.

Response	Three-drug regimen (n = 31) (%)	Two-drug regimens (n = 88) (%)
Complete response (CR)	0	0
Partial response (PR)	13 (41.9)	33 (37.5)
Stable disease (SD)	10 (32.3)	35 (39.8)
Progressive disease (PD)	8 (25.8)	20 (22.7)
Resectability achieved	10 (32.3)	23 (26.1)
Resectability not achieved	21 (67.7)	65 (73.9)
Grade 3–4 toxicity
Anaemia	3 (9.7)	23 (26.1)
Febrile neutropenia	6 (19.4)	9 (10.2)
Thrombocytopenia	0	5 (5.7)
Vomiting	1 (3.2)	3 (3.4)
Diarrhoea	3 (9.7)	4 (4.6)
Cardiac event	0	1 (1.1)