Table 3.

Correlation between left-ventricular reverse remodelling (ΔESV) and baseline electromechanical variables

	Spearman’s rho (P-value)	AUC (95% CI)
EF	0.16 (0.25)	0.59 (0.44–0.74)
QRS duration	−0.13 (0.35)	0.64 (0.48–0.78)
TST	0.42 (<0.01)	0.68 (0.51–0.81)
TLVAT	−0.68 (<0.01)	0.87 (0.75–0.95)
TST/TLVAT	0.56 (<0.01)	0.74 (0.58–0.86)
TLVMT	−0.08 (0.56)	0.60 (0.45–0.73)
SSI	0.41 (<0.01)	0.81 (0.68–0.91)
EM coupling	−0.09 (0.54)	0.51 (0.33–0.68)
Scar	−0.27 (0.03)	0.71 (0.56–0.87)

Receiver operating characteristic analysis for electromechanical measurements in identifying significant response to CRT (ΔESV > 15%). Positive rho values indicate a larger reduction in ESV with increasing value of the related variable.

AUC, area under the curve; CI, confidence interval; EF, ejection fraction; EM coupling: Pearson’s R of TD-TPS; SSI, systolic stretch index; TLVAT, total left-ventricular activation time; TLVMT, total left-ventricular mechanical time; TD, time of depolarization; TPS, time-to-peak shortening; TST, transseptal time.