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. 2022 Oct 17;30(2):267–276. doi: 10.1038/s41417-022-00541-7

Fig. 5. cSNX1.3 inhibits nuclear EGFR and survival signaling.

Fig. 5

A MDA-MB-468 cells were serum starved overnight then incubated with 20 ng/mL EGF and either cPTD4 or cSNX1.3 for 2 h. Cells were then fractionated and verified by HSP90 cytosolic protein, Bap31 membrane protein, or HDAC nuclear protein. B BT20 mammospheres were grown for 1 week in the presence of either vehicle, cPTD4, or cSNX1.3 and trypsinized, counted and replated. After the second week, the number of secondary mammospheres were counted.