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. 2023 Jan 18;24(1):52–56. doi: 10.1038/s41435-023-00194-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Expression of CYP11A1, CYP11B1 and HSD11B1 was assessed in tissue sections of non-small cell lung carcinoma (NSCLC, SCC = squamous cell carcinoma, AC = adenocarcinoma) and small cell lung carcinomas (SCLC, t.NET = typical neuroendocrine tumors) by RT-qPCR. Violin plots of n = 5–8 tumor samples are shown. B Immunohistochemistry analysis of 11-β hydroxysteroid dehydrogenase 1 (11-βHSD1) and 11-β hydroxylase (11-βOH) in tissue sections of squamous cell carcinoma (NSCLC) and typical neuroendocrine tumor (SCLC). H&E stainings and Rb IgG isotype controls are shown for comparison. Scale bar = 200 µm. Inlays show magnifications.