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. 2022 Jul 1;30(1-2):150–159. doi: 10.1038/s41434-022-00353-2

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Samples from a total of 120 healthy donor from different regions within the United States were evaluated. Each dot represents the normalized response (NR) from a donor. The green dashed line represents a clinical cutoff of 0.34. FL Florida, TN Tennessee, KY Kentucky, HI Hawaii, WA Washington, NY New York, OH Ohio, N Number. B Samples from a total of 62 pediatric donor with ages ranging from less than 1 to 12 were evaluated. Each dot represents the NR from a donor and each age group with a different symbol. The green dashed line represents a clinical cutoff of 0.34; N = Number. C 24 subjects across different clinical trials had blood re-drawn and reanalyzed during screening period. Black dots represent the initial analysis and magenta squares represent the analysis from a new blood collection. The green dashed line represents a clinical cutoff of 0.34.