Fig. 3. Crosslink support for predicted complex models.
a, The numbers and ratios of predicted structures having crosslink information for pairs of residues that bridge the two proteins in the predicted structure, broken down by the crosslinks that satisfy their expected maximal distance and by the predicted quality of the model (pDockQ). b–e, Examples of predicted structures of high confidence, with no previous structural information and supported by at least one crosslink (indicated with blue line): ERLIN1/ERLIN2 complex (b), IMMT and CHCHD3, components of the mitochondrial inner membrane MICOS complex (c), the complex of transfer RNA-guanine-N(7)-methyltransferase (METTL) with its noncatalytic subunit (WDR4) (d) and the heterogeneous nuclear ribonucleoprotein C (HNRNPC) and the RNA-binding protein, RALY (e).