Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 3;14:1145268. doi: 10.3389/fimmu.2023.1145268

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Kapetanakis and Busson

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Structural types of galectins. Galectins are categorized in three distinct groups, based on their structure. The first group contains members bearing a single carbohydrate recognition domain (CRD), while the second comprises of members with two CRDs, connected by a short peptide sequence (tandem repeat-type galectins). Galectin-3 is the sole member of the third group, as it combines a single CRD with a unique amino-terminal non-lectin domain (chimera-type galectin). Members of groups 1 and 3, bearing a single CRD, are able to polymerize, exhibiting new and distinct functional features compared to their monomeric forms (5).