Table 3.
Factors influencing the risk of diabetes in patients with prediabetes analyzed by univariate Cox proportional hazards regression.
| Exposure | Characteristics | HR (95%CI) | P-value |
|---|---|---|---|
| Age (years) | 49.292 ± 13.819 | 1.031 (1.028, 1.034) | < 0.001 |
| Sex | |||
| Male | 16,734 (66.197%) | Ref | |
| Female | 8,545 (33.803%) | 0.835 (0.766, 0.910) | < 0.001 |
| BMI (kg/m2) | 24.758 ± 3.265 | 1.119 (1.106, 1.132) | < 0.001 |
| SBP (mmHg) | 127.169 ± 17.586 | 1.015 (1.013, 1.017) | < 0.001 |
| DBP (mmHg) | 78.377 ± 11.135 | 1.017 (1.014, 1.020) | < 0.001 |
| FPG (mmol/L) | 5.945 ± 0.317 | 9.796 (8.889, 10.795) | < 0.001 |
| TG (mmol/L) | 1.410 (0.960–2.110) | 1.116 (1.096, 1.137) | < 0.001 |
| TyG | 8.835 ± 0.619 | 1.800 (1.700, 1.907) | < 0.001 |
| TyG-BMI | 219.465 ± 37.051 | 1.012 (1.011, 1.013) | < 0.001 |
| TC (mmol/L) | 4.975 ± 0.957 | 1.082 (1.040, 1.125) | < 0.001 |
| HDL-c(mmol/L) | 1.330 ± 0.303 | 1.246 (1.097, 1.416) | < 0.001 |
| LDL-c (mmol/L) | 2.886 ± 0.724 | 1.064 (1.010, 1.122) | 0.021 |
| ALT (U/L) | 22.000 (15.400–33.000) | 1.005 (1.004, 1.006) | < 0.001 |
| AST (U/L) | 26.328 ± 11.927 | 1.011 (1.009, 1.012) | < 0.001 |
| BUN (mmol/L) | 4.991 ± 1.251 | 1.051 (1.019, 1.083) | 0.002 |
| Scr (μmol/L) | 72.735 ± 15.988 | 1.001 (0.999, 1.004) | 0.392 |
| Smoking status | |||
| Current smoker | 5,715 (22.608%) | Ref | |
| Ever smoker | 1,034 (4.090%) | 1.059 (0.878, 1.276) | 0.550 |
| Never smoker | 18,530 (73.302%) | 0.823 (0.754, 0.899) | < 0.001 |
| Drinking status | |||
| Current drinker | 924 (3.655%) | Ref | |
| Ever drinker | 3,871 (15.313%) | 0.797 (0.650, 0.977) | 0.029 |
| Never drinker | 20,484 (81.032%) | 0.793 (0.659, 0.953) | 0.013 |
| Family history of diabetes | |||
| No | 24,654 (97.528%) | Ref | |
| Yes | 625 (2.472%) | 1.446 (1.191, 1.754) | < 0.001 |
Continuous variables were summarized as mean (SD) or medians (quartile interval); categorical variables were displayed as percentage (%).
FPG, fasting plasma glucose; BMI, body mass index; DBP, diastolic blood pressure; TC, total cholesterol, SBP, systolic blood pressure; TG triglyceride; ALT, alanine aminotransferase; TyG, the triglyceride-glucose index; TyG-BMI, triglyceride glucose-body mass index; BUN, blood urea nitrogen; LDL-c, low-density lipid cholesterol; Scr, serum creatinine, HDL-c, high-density lipoprotein cholesterol; AST aspartate aminotransferase.