Fig. 5.

A 49-year-old woman with subsolid nodule growth after long-term follow-up CT. a Baseline CT. Transverse plain CT of a pure ground-glass nodule in the right lower lobe. The nodule size (longest diameter) was 8 mm on transverse CT images. b Follow-up CT obtained 5 years after baseline. The pure ground-glass nodule was stable. c Follow-up CT obtained 6 years after the baseline CT. A new solid component appeared in the nodule, and its size decreased from 8 to 6 mm. The growing nodule was a minimally invasive adenocarcinoma, as confirmed by pathology