Table 1.

The clinical data and predominant laboratory investigations of four Chinese patients.

Patient	Patient1	Patient2	Patient 3	Patient 4
			Siblings
Gender	Female	Female	Male	Male
Age	6 months	3 years	8 years	15 years
Onset age	2 days	5 days	3 days	3 days
Presenting symptoms	Jaundice	Jaundice	Jaundice	Jaundice
Developmental delay	None	None	None	None
Other manifestation	Sepsis	None	Recurrent respiratory tract infections	Recurrent respiratory tract infections
	Entericadenovirus infection			EBV infection
	Respiratory tract infections			CMV infection
Alanine aminotransferase (7–40 IU/L)	75.65	138.1	110	445.4
Aspartate aminotransferase (0–40 IU/L)	197.01	215.3	141	170.9
Alkaline phosphatase (54–369 IU/L)	508.48	675	811	557
γ-glutamyl transpeptidase (8-57 IU/L)	956.71	832	390	1042
Total bilirubin (5.1-17.1μmol/L)	111.4	193.1	175.2	236.3
Direct bilirubin (0-6 μmol/L)	90.5	164.7	108.6	165.6
Total bile acid (0-10μmol/L)	321.5	91.6	304.4	NA
MRCP	NA	NA	Multiple cystic dilatations of intrahepatic bile ducts	NA
Laparoscopic cholangiography	Bile duct patency	The hilar bile duct was clouded and bile duct was unobstructed	Hepatobiliary isotope imaging excluded biliary atresia	NA

MRCP, magnetic resonance cholangiopancreatography; NA, not available.