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. 2022 Sep 30;33(3):2209–2217. doi: 10.1007/s00330-022-09115-5

Table 2.

Characteristics of patients diagnosed with contralateral ductal carcinoma in situ (DCIS) after primary DCIS by MRI use and moment of detection

MRI group MRI group Age-matched controls
Synchronous
(n = 12)
Metachronous
(n = 28)
p value$ Total
(n = 40)
Total
(n = 24)
p value
Age at diagnosis, median (IQR), years 51 (40–56) 50 (46–58) 0.61 51 (45–57) 53 (49–66) 0.03
Grade, n (%) 0.06 0.48
Low 4 (36%) 4 (15%) 8 (22%) 8 (35%)
Intermediate 6 (55%) 10 (39%) 16 (43%) 7 (30%)
High 1 (9%) 12 (46%) 13 (35%) 8 (35%)
Unknown n = 1 n = 2 n = 3 n = 1
Surgery, n (%) 11 (92%) 26 (93%) 1.00 37 (93%) 23 (96%) 0.52
BCS 1 (8%) 13 (46%) 14 (35%) 12 (50%)
Mastectomy 10 (83%) 13 (46%) 0.04 23 (58%) 11 (46%) 0.21
None 1 (8%) 2 (7%) 3 (8%) 1 (4%)
Radiotherapy, n (%) 1 (8%) 9 (32%) 0.23 10 (25%) 6 (25%) 1.00

BCS breast-conserving surgery, IQR interquartile range

$Comparison of synchronous with metachronous DCIS in the MRI group

Comparison of all contralateral DCIS in the MRI group versus the age-matched controls