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. 2023 Feb 3;10:1050255. doi: 10.3389/fmed.2023.1050255

Table 3.

AKI prediction model for all care settings.

Reference Modeling data sources Data volume Model performance AUC value External verification Machine learning methods Diagnostic criteria
Data source Data volume Model performance (AUROC)
Koyner et al. (29) University of Chicago Hospital, US 121,158 24 h in advance 0.90 No Gradient boosting machine KDIGO: Creatinine
48 h in advance 0.87
Dialysis 48 h in advance 0.96
Mohamadlou et al. (32) Stanford Medical Center, US 48,582 Onset of illness 0.872 MIMIC-III 19,737 Onset of illness 0.841 Boosting decision trees NHS-AKI: Creatinine
12 h in advance 0.800 12 h in advance 0.749
24 h in advance 0.795 24 h in advance 0.758
48 h in advance 0.761 48 h in advance 0.707
72 h in advance 0.728 72 h in advance 0.674
He et al. (33) University of Kansas Health System—KUHS 96,590 24 h in advance 0.744 No Logistic regression Random forest KDIGO: Creatinine
Any time 0.734
Day 1 after admission 0.764
Day 2 after admission 0.764
Kate et al. (31) Aurora Health Care (15) hospitals 25,521 0.743 No Logistic regression
Support vector machines
Decision trees
Naive Bayes
AKIN: Creatinine
Cronin et al. (28) US Department of Veterans Affairs 1,620,898 AKI I 0.746–0.758 No Logistc regression LASSO regression Random forest KDIGO: Creatinine
AKI II 0.714–0.720
Dialysis 0.823–0.825
Churpek et al. (34) University of Chicago (UC) 48,463 48 h in advance AKI II 0.86 NorthShore University Health System (NUS) 246,895 0.86 Gradient boosting machine KDIGO: Creatinine
Loyola University
Medical Center (LUMC)
200,613 0.85
Kim et al. (35) Seoul National University Bundang Hospital, South Korea 69,081 AKI I 0.88 Seoul National University Hospital, South Korea 72,352 AKI I 0.84 Recurrent neural network
Extreme gradient boosting
KDIGO: Creatinine
AKI II 0.93 AKI II 0.90
Cheng et al. (36) University of Kansas Medical Center - KUMC 48,955 0.76 No Logistic regression
Random forest
Adaptive boosting
KDIGO: Creatinine
Tomasev et al. (30) US Department of Veterans Affairs 703,782 Any AKI 0.921 No Recurrent neural network KDIGO: Creatinine
AKI II III 0.957
AKI III 0.980

KDIGO, Kidney Disease: Improving Global Outcomes; AKIN, Acute Kidney Injury Network. NHS, National Health Service; MIMIC-III, Medical Information Mart for Intensive Care III.