Skip to main content
. 2023 Jan 7;40(2):289–299. doi: 10.1007/s10815-022-02695-7

Table 2.

Study data comparing patient age, euploid rate, aneuploid rate and simple mosaic rate between subjective NGS and AI 1.0 or AI 2.0 using SART age group stratification. Listed confidence intervals describe the differences in AI means vs the subjective NGS mean

Maternal age (yr) Platform Cases (n) Euploid (%) p 95% CI Aneuploid (%) p 95% CI Simple mosaic (%) p 95% CI
 < 35 Subjective 715 43.6 - 36.2 - 20.2 - -
AI 1.0 221 53.3*  < 0.001 0.051–0.142 31.1* 0.047  − 0.101–0.001 15.6* 0.004  − 0.079–0.013
AI 2.0 151 51.3* 0.002 0.025–0.129 33.8 0.588  − 0.083–0.035 14.9* 0.005  − .092–0.014
35–37 Subjective 693 35.6 - 47.2 - 17.2 - -
AI 1.0 170 41.9* 0.001 0.013–0.113 42.8 0.152  − 0.100–0.012 15.3 0.440  − 0.056–0.018
AI 2.0 155 46.6*  < 0.001 0.058–0.162 40.4* 0.018  − 0.126–0.010 13.0 0.300  − 0.081–0.003
38–40 Subjective 885 25.6 - 61.8 - 12.7 - -
AI 1.0 237 34.5*  < 0.001 0.046–0.132 57.4 0.078  − 0.092–0.004 8.2* 0.003  − 0.077–0.013
AI 2.0 159 30.5 0.058  − 0.001–0.010 60.1 0.722  − 0.074–0.038 9.5 0.108  − 0.069–0.005
41 Subjective 317 16.2 - 74.7 - 9.2 - -
AI 1.0 67 23.4 0.101  − 0.011–0.157 69.7 0.412  − 0.144–0.044 6.7 0.601  − 0.087–0.037
AI 2.0 74 20.6 0.345  − 0.031–0.119 73.6 0.947  − 0.095–0.073 5.8 0.318  − 0.090–0.053
42 Subjective 252 13.4 - 80.8 - 5.9 - -
AI 1.0 56 8.9 0.426  − 0.131–0.041 87.1 0.268  − 0.034–0.160 4.0 0.756  − 0.083–0.045
AI 2.0 37 14.9 0.934  − 0.088–0.118 81.4 0.991  − 0.109–0.121 3.6 0.749  − 0.099–0.053
 > 42 Subjective 362 17.5 - 73.5 - 9.0 - -
AI 1.0 72 12.0 0.114  − 0.131–0.041 79.7 0.194  − 0.023–0.147 8.3 0.952  − 0.063–0.049
AI 2.0 55 3.7*  < 0.001  − 0.223–0.053 95.2*  < 0.001 0.122–0.313 1.2* 0.012  − 0.141–0.015

*p < 0.05 compared to subjective