Table 3.
Topological parameter analysis of key targets.
| Name | Closeness | Betweenness | Degree |
|---|---|---|---|
| EGFR | 155.91667 | 21055.22881 | 87 |
| CASP3 | 138.91667 | 13581.81055 | 61 |
| IL6 | 136.0 | 11100.0022 | 53 |
| FOS | 132.66667 | 9254.88492 | 50 |
| ESR1 | 127.58333 | 5203.38585 | 47 |
| AR | 123.5 | 6788.10848 | 45 |
| MYC | 121.5 | 2737.21043 | 26 |
| ICAM1 | 104.66667 | 1694.87097 | 26 |
| ESR2 | 110.83333 | 866.28027 | 19 |
| BIRC5 | 104.35 | 2468.86776 | 18 |
| NR3C1 | 111.35 | 1192.98489 | 17 |
| TP53 | 116.85 | 795.40972 | 12 |
| STAT3 | 117.18333 | 1038.66281 | 12 |
| HSPB1 | 106.68333 | 1341.56512 | 10 |
| SRC | 110.66667 | 3322.67413 | 8 |
| MAPK14 | 113.01667 | 266.80844 | 8 |
| JUN | 117.58333 | 5100.94748 | 8 |
| TNF | 112.35 | 704.28349 | 8 |
| VEGFA | 110.01667 | 982.86802 | 8 |
| RELA | 105.51667 | 314.52161 | 8 |
| MAPK1 | 111.01667 | 249.58642 | 7 |
| MAPK3 | 111.01667 | 249.58642 | 7 |
| MAPK8 | 108.35 | 247.61036 | 7 |