Table 3. Whole Body MRI Protocol from MY-RADS.
| No. | Sequence | Core Clinical Protocol (30 min) | Comprehensive Assessment (50 min) | |
|---|---|---|---|---|
| 1 | Whole spine: sagittal, T1-WI, FSE, section thickness 4–5 mm | O | O | |
| 2 | Whole spine: sagittal, T2, STIR or FS T2-WI, section thickness 4–5 mm | O | O | |
| 3 | Whole body (vertex to knee): T1-WI, GE Dixon. Fat and water image reconstruction with fat fraction maps (FF = F/(F + W)/100%) | Axial or coronal (5 mm) | Axial and coronal | |
| 4 | Whole body: axial, diffusion-weighted, STIR FS, 5 mm contiguous sectioning, multiple stations | Two b-values (50–100 sec/mm2, 800–900 sec/mm2) | Three b-values (+500–600 sec/mm2) | |
| • ADC calculations with monoexponetial data fitting | ||||
| • 3D MIP reconstructions of highest b-value images | ||||
| 5 | Whole body: axial, T2WI, FSE w/o FS, 5 mm contiguous sectioning, preferably matching the DWI | Optional | O | |
| 6 | Regional assessments such as symptomatic or known sites, suspected cord compression/nerve root involvement/extramedullary disease | Usually not | Optional | |
Adapted from Messiou et al. Radiology 2019;291:5-13 (20).
ADC = apparent diffusion coefficient, DWI = diffusion weighted imaging, FS = fat suppression, FSE = fast spin-echo, GE = gradient-echo, MIP = maximum intensity projection, MY-RADS = myeloma response assessment and diagnosis system, STIR = short inversion time inversion-recovery, WI = weighted imaging