Table 4.

Evaluation of curcumin's beneficial effects in the model insects and organisms.

S. No.	Study	Effective dosage	Insect	Main findings	References
1	Curcumin stimulates biochemical mechanisms of Apis Mellifera resistance and extends the apian life span	3 μg/ml	Apis mellifera (Western honey bee)	Curcumin increased apian life span, increased oxidation related protein levels and decreased DNA-methylation	(132)
2	Curcumin supplementation increases survival and lifespan in Drosophila under heat stress conditions	0.2 mg/g	Drosophila melanogaster (Fruit fly)	Curcumin fed drosophila were observed to have increased survival rates with enhance thermal tolerance	(133)
3	Developmental and behavioral toxicity induced by acrylamide exposure and amelioration using phytochemicals in Drosophila melanogaster	10 μM	Drosophila melanogaster (Fruit fly)	Curcumin along with another phytochemical have the potential in reducing acrylamide induced toxicity in Drosophila melanogaster	(134)
4	Regulation of heme oxygenase and its cross-talks with apoptosis and autophagy under different conditions in Drosophila	1 mg/mL (of the medium)	Drosophila melanogaster (Fruit fly)	Curcumin induced increased expression levels of heme oxygenase in drosophila brain	(135)
5	Screening bioactive food compounds in honey bees suggests curcumin blocks alcohol-induced damage to longevity and DNA methylation	100 μg/ml	Apis mellifera (Western honey bee)	Lifespan shortening caused by ethanol intake was restored when curcumin was co-administered through DNA methylation changes	(136)
6	Impacts of diverse natural products on honey bee viral loads and health	100 ppm	Apis mellifera (Western honey bee)	Curcumin fed bees showed low levels of Gilliamella, a honeybee bacterial symbiont	(137)