Figure 10.

Relative mRNA quantification of hepatic xenobiotic metabolism genes regulated by CAR, PXR, and PPARα in NAFLD Study. Relative gene expression of genes involved in lipogenesis; A, Cyp2c55, B, Cyp2b10, C, Cyp4a10, and D, Cyp3a11. A symbol * placed on each column identifies significant differences compared to vehicle of same diet, # placed on each column identifies significant differences compared to low-fat diet in the same treatment duration. Data are presented as mean ± SD (n = 6–7/group), analyzed using 1-way ANOVA followed by Tukey’s multiple comparisons test. A p < .05 was considered significant.