Figure 3.

Relative mRNA quantification of FXR target genes in an acute treatment with Myclobutanil study with or without GW4064. A, Hepatic (Cyp7a1, Lcn13, Ostβ, and Shp), B, ileal (Fgf15, Shp, Tgr5, and Ostβ). A symbol * placed on each column identifies significant differences compared to vehicle, # placed on each column identifies significant differences compared to GW4064. Data are presented as mean ± SD (n = 3–7/group), analyzed using 1-way ANOVA followed by Tukey’s multiple comparisons test. A p < .05 was considered significant.