Table 1. Patient Demographic Characteristics and Disease Characteristics.
| Characteristic | No. (%) (N = 425) |
|---|---|
| Age at start of the therapy, median (range), y | 61 (20-92) |
| BMI, median (range) | 24.4 (15.1-44.8) |
| Ongoing treatment | |
| Chemotherapy | 391 (92.0) |
| Radiotherapy | 3 (0.7) |
| Surgery | 1 (0.2) |
| Concomitant chemotherapy and radiotherapy | 13 (3.1) |
| Endocrine therapy | 2 (0.5) |
| Target therapy | 8 (1.9) |
| Chemotherapy and endocrine therapy | 3 (0.7) |
| Sequential chemotherapy and radiotherapy | 1 (0.2) |
| Chemotherapy and surgery | 2 (0.5) |
| Locoregional treatment | 1 (0.2) |
| Tumor site | |
| Colon | 54 (12.7) |
| Rectum | 46 (10.8) |
| Breast | 77 (18.1) |
| Gastric or early gastric cancer | 70 (16.5) |
| Lung | 47 (11.1) |
| Pancreas | 32 (7.5) |
| Biliary tract | 13 (3.1) |
| Bladder or urinary tracts | 3 (0.7) |
| Prostate | 1 (0.2) |
| Mesothelioma | 2 (0.5) |
| Head and neck | 7 (1.6) |
| Gynecologic or urological | 26 (6.1) |
| Anus | 4 (0.9) |
| Sarcoma | 2 (0.5) |
| Esophagus | 7 (1.6) |
| Skin | 2 (0.5) |
| Neuroendocrine tumor (thoracic and GEP) | 24 (5.6) |
| Appendix | 1 (0.2) |
| Unknown | 7 (1.6) |
| Variables involved in Khorana score calculation and Khorana score | |
| Tumor risk | |
| Low | 247 (58.1) |
| High | 76 (17.9) |
| Very high | 102 (24.0) |
| Hemoglobin level <10 g/dL or use of red blood cell growth factors | |
| No | 401 (94.4) |
| Yes | 24 (5.6) |
| Prechemotherapy leukocyte count >11 000/µL | |
| No | 384 (90.4) |
| Yes | 41 (9.6) |
| Prechemotherapy platelet count ≥350 × 103/µL | |
| No | 343 (80.7) |
| Yes | 82 (19.3) |
| BMI ≥35 | |
| No | 408 (96.0) |
| Yes | 17 (4.0) |
| Khorana score | |
| 0 | 181 (42.6) |
| 1 | 92 (21.6) |
| 2 | 114 (26.8) |
| 3 | 29 (6.8) |
| 4 | 8 (1.9) |
| 5 | 1 (0.2) |
| Variables involved in ONKOTEV score calculation and ONKOTEV score | |
| Khorana score | |
| ≤2 | 387 (91.1) |
| >2 | 38 (8.9) |
| Previous venous thromboembolism | |
| No | 394 (92.7) |
| Yes | 31 (7.3) |
| Metastatic disease | |
| No | 136 (32.0) |
| Yes | 289 (68.0) |
| Macroscopic vascular or lymphatic compression | |
| No | 387 (91.1) |
| Yes | 38 (8.9) |
| ONKOTEV score | |
| 0 | 116 (27.3) |
| 1 | 234 (55.1) |
| 2 | 64 (15.1) |
| 3 | 10 (2.4) |
| 4 | 1 (0.2) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); GEP, gastroenteropancreatic.
SI conversion factors: To convert hemoglobin to grams per liter, multiply by 10; leukocytes to ×109/L, multiply by 0.001; and platelets to ×109/L, multiply by 1.0.