Fig. 6.

High levels of GPX2 expression correlated with poor efficiency to lenvatinib treatment in HCC patients. (A). Representative immunohistochemical images of GPX2 protein expression in HCC specimens (left). Images of CT or MR scans before and after therapy of lenvatinib in HCC patients. (Red arrow point for the lesions in the liver, and yellow arrow point for the tumor thrombus in vascular). (B) Correlation analysis of GPX2 expression and lenvatinib efficiency in our cohort. (C) Percentage changes of the diameters of lesions after lenvatinib treatment compared with baseline according to mRECIST. The Chi-square test was used to analyse the correlation between the expression of GPX2 and lenvatinib response. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)