Table 2.
Cox Proportional Hazard Regression Analysis of various prognostic characteristics for RFS (recurrence-free survival) in patients with HCC.
|
Simple regression analysis (RFS) |
Multiple regression analysis (RFS) |
|||||
|---|---|---|---|---|---|---|
| β (SE) | HR (95% CI) | P value | β (SE) | HR (95% CI) | P value | |
| Age | 0.121 (0.282) | 1.129 (0.649–1.961) | 0.668 | |||
| Gender | −0.303 (0.378) | 0.739 (0.352–1.550) | 0.423 | |||
| AFP(μg/L） | 0.463 (0.248) | 1.589 (0.977–2.583) | 0.062 | |||
| Child-Pugh | 0.614 (0.434) | 1.848 (0.789–4.327) | 0.157 | |||
| HBV infection | 0.308 (0.344) | 1.360 (0.692–2.671) | 0.372 | |||
| BCLC stage | 0.961 (0.226) | 2.613 (1.679–4.049) | <0.001 | 0.826 (0.304) | 2.284 (1.259–4.141) | 0.007 |
| TNM stage | 0.605 (0.171) | 1.831 (1.309–2.562) | <0.001 | 0.064 (0.279) | 1.066 (0.617–1.842) | 0.819 |
| Histological grade | 0.185 (0.178) | 1.203 (0.849–1.705) | 0.299 | |||
| Tumor size | 0.943 (0.304) | 2.567 (1.414–4.662) | 0.002 | 0.096 (0.442) | 1.101 (0.463–2.517) | 0.828 |
| GPX2 expression | 0.367 (0.247) | 1.444 (0.889–2.344) | 0.138 | |||
| Vascular invasion | 0.726 (0.311) | 2.067 (1.124–3.802) | 0.019 | 0.460 (0.314) | 1.584 (0.855–2.933) | 0.143 |
Abbreviation: β, regression coefficient; SE, standard error; HR, Hazard Ratio; CI, Confidence Interval.