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. 2023 Feb 17;14:910. doi: 10.1038/s41467-023-36586-x

Fig. 6. Working model for the role of mRNA stability in transcriptional memory.

Fig. 6

Induction memory and repression memory genes present different intrinsic susceptibilities to nuclear mRNA decay. After galactose priming, the abundance of nuclear degradation machinery decreases. Thus, although there is a global increase in absolute mRNA stability, the relative stability of induction memory genes increases and the one of the repression memory genes decreases. These favors enhanced induction/repression responses in primed cells.