Table 5.
Total Number of Mutations for each Virus, Divided by Synonymous and Nonsynonymous
| Virus—strain/clade | Total missense mutations | Total synonymous mutations | Date range | Number of sequences |
|---|---|---|---|---|
| SARS-CoV-2, Spike- Alpha | 8,226,073 | 1,358,712 | 12/2019–02/2022 | 496,938 |
| SARS-CoV-2, Spike—Beta/mu | 1,721,205 | 382,138 | 12/2019–04/2022 | 207,758 |
| SARS-CoV-2, Spike—Delta | 27,031,401 | 1,983,386 | 12/2019–06/2022 | 1,408,083 |
| SARS-CoV-2, Spike—Gamma/Lambda | 3,138,059 | 662,222 | 12/2019–05/2022 | 264,741 |
| SARS-CoV-2, Spike—Omicron | 46,728,781 | 9,935,369 | 12/2019–07/2022 | 1,195,971 |
| Influenza, HA- H1N1 | 427,034 | 664,436 | 01/1989–02/2019 | 15,080 |
| Influenza, HA—H3N2 | 841,792 | 1,375,395 | 04/1982–06/2021 | 29,045 |
| Dengue virus, E—Dengue 1 | 24,369 | 163,741 | 10/2019–01/2005 | 1676 |
| MERS-CoV, Spike | 1191 | 6660 | 12/2008–04/2019 | 531 |