Table 3. Enriched Biological Pathways for 17 Proteins with Significant Differences in Male vs Female Coronas of Mesoporous NPs.
| GO term | biological process | number of proteins | strength | P value |
|---|---|---|---|---|
| GO:0006957 | complement activation, alternative pathway | 3 | 2.59 | 0.0002 |
| GO:0019835 | cytolysis | 4 | 2.33 | 5.38 × 10–5 |
| GO:0006958 | complement activation, classical pathway | 4 | 2.20 | 6.74 × 10–5 |
| GO:0006959 | humoral immune response | 6 | 1.66 | 5.38 × 10–5 |
| GO:0042742 | defense response to bacterium | 4 | 1.30 | 0.0209 |
| GO:0050778 | positive regulation of immune response | 5 | 1.16 | 0.0113 |
| GO:0045087 | innate immune response | 6 | 1.14 | 0.0023 |
| GO:0098542 | defense response to other organisms | 8 | 1.13 | 0.0001 |
| GO:0006955 | immune response | 7 | 0.97 | 0.0035 |
| GO:0002376 | immune system process | 8 | 0.75 | 0.0151 |
| GO:0009605 | response to external stimulus | 9 | 0.72 | 0.0073 |
| GO:0048518 | positive regulation of biological process | 13 | 0.46 | 0.0140 |
| GO:0050896 | response to stimulus | 14 | 0.42 | 0.0120 |